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林辰涛,男,1982年毕业于中国华南热带农业大学,获农学学士学位;1987年获美国爱荷华州立大学植物学硕士学位;1992年获美国密歇根州立大学遗传学博士学位;1992.6至1996.6
在美国宾夕法尼亚大学做博士后研究工作。1985.9至1987.9在爱荷华州立大学做助理研究员;1987.9至1992.6
在密歇根州立大学做助理研究员;1992.6至1996.6在宾夕法尼亚大学生物系作博士后;1996.7至2000.12在加州大学洛杉矶分校分子、细胞和发育生物学系任副教授;1996.7至今在加州大学洛杉矶分校分子、细胞和发育生物学系任教授2003年被中国农科院聘为一级岗位杰出人才。
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林辰涛教授为植物光信号传导及蓝光受体研究领域的国际权威。其在该领域做出的主要成果包括:首次发现了植物蓝光受体隐花素(CRY1)的色素团化学成分;第2种隐花素CRY2以及在调控光周期开花中的作用;钙离子结合蛋白在光信号协同调节中的地位;隐花素磷酸化以及在光信号传递中的功能;隐花素信号传递的光诱导蛋白相互作用假设以及作为其直接证据的第一个植物CRY特异的信号传递转录因子基因CIB1的功能与作用机制;及大豆蓝光受体CRY1在控制大豆成熟期以及纬度分布上的作用。主持人实验室为受到美国国家卫生研究院(NIH)连续资助十多年的为数不多的植物科学实验室之一,其在Science、Nature、PNAS和Plant
cell等刊物上发表50多篇研究论文。主持人于2003年开始在中国农科院开展农作物基因功能的合作研究。并于2009年成为中国农科院高层次人才(千人计划)入选者。
研究方向与主要研究内容:
水稻功能基因组学。主要采用显性变异基因组学与蛋白组学等方法研究水稻转录调节机理,以及其在水稻产量、氮肥利用率及抗逆性等重要农艺性状中的作用与功能。
主要研究成果与业绩:
1.
Yu, X., Sayegh, R., Maymon, M., Warpeha, K.,
Klejnot, J., Yang, H., Huang, J., Lee, J., Kaufman, L.,
and Lin, C. (2009) Formation of nuclear bodies of Arabidopsis
CRY2 in response to blue light is associated with blue
light-dependent degradation of the photoreceptor Plant
Cell
21: 118–130.
2. Liu,
H. Yu, X., Li, K., Klejnot, J., Yang, H., Lisiero, D. and Lin,
C.
(2008) “Photoexcited CRY2 interacts with CIB1 to regulate
transcription and floral initiation in Arabidopsis”,
Science 322: 1535-1539
3. Zhang
Q, Li, H., Li, R., Hu, R., Fan, C., Chen, F., Wang, Z., Liu, X.,
Fu, Y., and Lin, C. (2008), Association of the circadian
rhythmic expression of GmCRY1a with a latitudinal cline in
photoperiodic flowering of soybean Proc Natl Acad Sci U S
A, 105:
21028–21033
4. Yu, X., Klejnot, J., Zhao, X., Shalitin
D., Maymon M., Yang H., Lee
J., Liu, X., Lopez,
J, and Lin, C. (2007). Arabidopsis cryptochrome 2
completes its post-translational “life cycle” in the nucleus.
Plant Cell 19: 3146-3156
5.
Yu X.,
Shalitin D., Liu X., Maymon M., Klejnot J., Yang H., Lopez J.,
Zhao X., Bendehakkalu K.T., Lin C., (2007) De-repression of the
NC80 motif is critical for the photoactivation of Arabidopsis
CRY2. Proc Natl Acad Sci U S A, 104: 7289–7294
6. Lin,
C. and Todo, T. (2005) “Cryptochromes” Genome Biology 6:220-228
7.Yu, X.,
and Lin, C. (2005) “Light regulation of flowering-time in
Arabidopsis” In W. Wada, K. Shimazaki, and M. Iino (Eds.) Light
Signaling in Plants, pp 235-331, Springer, Tokyo.
8.Mockler, T.C., Yu, X., Shalitin, D., Parikh, D., Michael,
T.P., Liou, J., Huang, J., Smith, Z., Alonso, J.M., Ecker, J.R.,
Chory, J., and Lin, C., (2004) “Regulation of flowering time in
Arabidopsis by K homology-domain proteins” Proc Natl Acad Sci U
S A 101:12759-12764.
9.Klejnot, J., and Lin, C. (2004). A CONSTANS experience brought
to light. Science 303, 965-966
10.Lin,
C. (2004). Photoreceptors and Associated Signaling II:
cryptochromes. In Encyclopedia of Plant and Crop Science, R.M.
Goodman, ed (New York: Marcel Dekker, Inc), pp. 885-888
11.Shalitin, C., Yu, X., Maymon, M., Mockler, T., and Lin, C.
(2003) “The blue light-dependent in vivo and in vitro
phosphorylation of Arabidopsis cryptochrome 1”. Plant Cell
15:2421-2429.
12.Lin,
C. and Shalitin, D. (2003) “Cryptochrome structure and signal
transduction”.
Annu. Rev. Plant
Biol.
54: 469-496.
13.Mockler, T., Yang, H., Yu, X., Parikh, D., Cheng, Y.C.,
Dolan, S., and Lin, C. (2003). “Regulation of photoperiodic
flowering by Arabidopsis photoreceptors”. Proc Natl Acad
Sci U S A 100, 2140-2145.
14.Shalitin, D., Yang, H., Mockler, T. C., Maymon, M., Guo, H.,
Whitelam, G. C., and Lin,
C. (2002) “Regulation of Arabidopsis cryptochrome 2 by
blue light-dependent phosphorylation”. Nature
417:763-767
15.Lin, C., (2002) Blue light receptors and signal
transduction. Plant Cell S207-S225.
16.Lin, C. (2002) Phototropin blue light receptors and
light-induced movement responses in plants. Science
295:759
17.Guo, H., Mockler, T., Duong, H., and Lin, C. (2001) SUB1, an
Arabidopsis Ca2+-binding protein involved in
cryptochrome and phytochrome co-action. Science
291:487-490
18.Lin, C. (2000) Plant blue-light receptors. Trends
Plant Sci. 5:337-342
19.Mockler, T. C., Guo, H., Yang, H., Duong, H., and Lin, C.
(1999) Antagonistic actions of the Arabidopsis cryptochromes and
phytochrome B in the regulation of floral induction.
Development 126:2073- 2082.
20.Guo, H., Yang, H., Mockler,T. C., and
Lin, C. (1998) Regulation of Flowering Time by
Arabidopsis Photoreceptors. Science
279:1360-1363.
21.Lin, C., Yang, H., Guo, H., Mockler, T. C., Chen, J. and
Cashmore, A. R. (1998) Enhancement of Blue-Light
Sensitivity of Arabidopsis Seedlings by a Blue Light Receptor
Cryptochrome 2. Proc. Natl. Acad. Sci. UAS
95:2686-2690.
22.Lin, C., Robertson, D.E., Ahmad, M., Reibaks, A., Jorns, M.,
Dutton, L., and Cashmore, A. R. (1995). Association of flavin
adenine dinucleotide with the Arabidopsis blue light receptor
CRY1. Science, 269:968-970.
23.Lin, C., Ahmad, M., Gordon, D., and Cashmore, A. (1995).
Expression of an Arabidopsis cryptochrome gene in transgenic
tobacco results in hypersensitivity to blue, UV-A, and green
light. Proc. Natl. Acad. Sci. USA, 92 (18):
8423-8427.
联系地址:100081 北京中关村南大街12号
联系电话:010-62136046
传真:01062136045
E-mail:clin@mcdb.ucla.edu
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